Webintestinal flora of Tsumura Suzuki Obese Diabetes (TSOD) mice was compared with that of Tsumura, Suzuki, Non Obesity (TSNO) mice in the present study. The TSOD mice showed typical type 2 diabetes symptoms, which were high-fat diet-independent. The TSOD and the TSNO mouse models were derived from the same strain, ddY. WebJun 26, 2024 · The TSOD mouse was originally established from an outbred ddY strain as an inbred strain with obesity and urinary glucose . The congenic mouse strain T.B-Nidd5/3 was developed and characterized previously (3,4). The GDF3 knockout mouse with a genetic background of C57BL/6J was described previously . C57BL/6N ...
Efficacy of Kaempferia parviflora in a mouse model of obesity …
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Genetic analysis of obese diabetes in the TSOD mouse
WebTSOD male mice exhibit both obesity and diabetes enabling that strain to be used in a cross with BALB/cAJcl to elucidate the genetic basis for the phenotype. (BALB/cAJcl x … WebOct 7, 2024 · Male Tsumura-Suzuki Obese Diabetes (TSOD) mice, a spontaneous metabolic syndrome model, develop non-alcoholic steatohepatitis and liver tumors by feeding on a standard mouse diet. Nearly 70% of liver tumors express glutamine synthetase (GS), a marker of hepatocellular carcinoma. In contrast, approximately 30% are GS-negative … WebDiabetes mellitus is a well known and important risk factor for cardiovascular diseases, including heart failure. A new model of Type 2 diabetes, Tsumura Suzuki Obese Diabetes … compare refrigerators 28 inch width