Mafb transcription factor

Author: esdg

August undefined, 2024

WebNov 13, 2024 · A mouse MafA BAC spanning the 5′ flanking regions 1–6 transcription control sequences necessary for directing islet cell–specific expression ( 31) was used to … WebFeb 1, 2006 · The MafB expression pattern is unique because no other known pancreatic transcription factor is expressed in only α- and β-cell progenitors and then becomes …

Entry - *608968 - MAF bZIP TRANSCRIPTION FACTOR B; MAFB

WebJul 1, 2002 · This work has shown that Maf proteins contain a highly conserved acidic transactivation domain (AD), and a bZIP region that mediates DNA‐binding activity, which plays key roles in vertebrate lens development. Background: Members of the Maf family, including L‐Maf, MafB and c‐Maf, are ‘basic region/leucine zipper’ (bZIP) transcription … WebMay 18, 2024 · MAFB has a pro-ser-thr-rich acidic transcription activation domain at its N terminus, followed by 2 histidine repeats, an extended homology region, a basic DNA-binding domain, and a C-terminal leucine zipper domain containing hydrophobic residues that form the zipper heptad repeats (LLLLYL). puckersley royton

pesquisa.bvsalud.org

WebSimply, the transcription factor Mafb was conditionally deleted in pancreatic progenitor cells under Mafa knockout condition (termed A0B Δpanc mice). A0B Δpanc mice displayed obvious hyperglycemia compared with the A0B2 and WT mice, at least 2 h following glucose administration ( Figure 2 ). WebSep 1, 2024 · MAFB is a basic leucine zipper (bZIP) transcription factor specifically expressed in macrophages. We have previously identified MAFB as a candidate marker … WebMar 22, 2016 · MafB, a transcription factor expressed selectively in macrophages, has important roles in some macrophage-related diseases, especially in atherosclerosis. In this study, we investigated the mechanism by which hematopoietic-specific MafB deficiency induces the development of obesity. puckers the lips

Frontiers Transcription factor MAFB controls type I and II …

WebNov 3, 2024 · MAFB is a transcription factor and a member of the large Maf family that is selectively expressed by monocytes and macrophages to induce monocyte–macrophage … WebA LncRNA-MAF/MAFB transcription factor network regulates epidermal differentiation: Organism: Homo sapiens: Experiment type: Expression profiling by array Genome binding/occupancy profiling by high throughput sequencing: Summary: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series : … pucker street dam niles michiganWebMay 15, 2014 · The large Maf transcription factors, MafA and MafB, are expressed with distinct spatial–temporal patterns in rodent islet cells. Analysis of Mafa−/− and pancreas-specific Mafa∆panc deletion mutant mice demonstrated a primary role for MafA in adult β-cell activity, different from the embryonic importance of MafB. sea towers newsletter

"WebMafB Transcription Factor (5) Macrophages (3) Glomerulosclerosis, Focal Segmental (2) " - Mafb transcription factor

Mafb transcription factor

MafB deficiency accelerates the development of obesity in mice

WebApr 4, 2024 · Gene ID: 9935, updated on 19-Feb-2024. Summary. The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in … WebDec 7, 2006 · We report that MafB negatively regulates RANKL-induced osteoclastogenesis by interfering with the DNA-binding domains of transcription factors including c-Fos, Mitf, and NFATc1, thereby inhibiting the transactivation of NFATc1 and OSCAR.

Did you know?

WebMay 18, 2024 · MAFB has a pro-ser-thr-rich acidic transcription activation domain at its N terminus, followed by 2 histidine repeats, an extended homology region, a basic DNA … WebMar 16, 2024 · MafB and c-Maf are b-ZIP transcription factors that belong to the same family of large Maf proteins 37 and can cooperate together in some contexts, such as in the regulation of macrophage self ...

WebJun 2, 2024 · Numerous reports have identified MAF BZIP Transcription Factor B (MAFB) to be present in human β-cells postnatally, while its expression is restricted to embryonic … WebMay 26, 2024 · Herein, we show that (1) Mef2c and Snap25 are positively regulated by Maf and Mafb to drive IN morphological maturation; (2) Maf and Mafb promote Mef2c expression which specifies parvalbumin (PV +) INs; (3) Elmo1, Igfbp4 and Mef2c are candidate markers of immature PV + hippocampal INs (HIN).

WebTranscription Factor MafB. The transcription factors MafB and c-Maf belong to a family of basic-leucine zipper (b-Zip) factors that bind DNA as dimers. From: Hematology (Seventh … WebTranscription Factor MafB. The transcription factors MafB and c-Maf belong to a family of basic-leucine zipper (b-Zip) factors that bind DNA as dimers. From: Hematology …

WebMaf transcription factors are a family of basic-leucine zipper transcription factors that are closely related to V-MAF ONCOGENE PROTEIN.

WebSep 26, 2024 · MAFB is an important transcription factor involved in lymphangiogenesis. Study provides insights to elucidate mechanisms of gene regulation through androgen response elements present in Mafb 3'UTR for a better understanding of the processes of urethral masculinization. sea towers owners associationWebThe bZIP protein MafA has been identified as the rat insulin promoter element 3b1 (RIPE3b1) factor ( Shieh and Tsai, 1991 ), which is a transcription factor that binds to the C1/RIPE3b1 element and positively regulates the transcriptional activity of the insulin promoters in mouse ( Matsuoka et al., 2003 ), rat ( Kajihara et al., 2003; Matsuoka ... pucker strainWebMar 23, 2024 · IL4I1 suppresses Th17 cell proliferation and promotes Treg differentiation. 21,22 FOS and FOSB encode transcription factors c-Fos and FosB, ... The microarray analysis also revealed that expression of the transcription factor MAFB was upregulated after OCH administration in all cohorts. sea towers marco islandWebPharos : Target Details - MAFB Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data pucker thesaurusWebHere we show that in mice, the transcription factors MafB and c-Maf repress a macrophage-specific enhancer repertoire associated with a gene network that controls self-renewal. Single-cell analysis revealed that, in vivo, proliferating resident macrophages can access this network by transient down-regulation of Maf transcription factors. pucker strain infoWebImages Epitopes New Antibodies › by Gene › by Protein › MAFB Antibodies MAFB Antibodies Antibodies that detect MAFB can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and Immunoprecipitation. These antibodies target MAFB in Human, Mouse and Rat samples. puckers pubWebA second transcription factor, MafB (also called Kreisler after the mouse bearing a mutation in this gene), is expressed in the podocyte beginning in the capillary loop stage (around E14.5) and extending into adulthood ( Sadl et al 2002 ). Mice homozygous for a genetic mutation in MafB exhibit developmental defects in the hindbrain and kidney. sea towers mexico