Ferm domain-containing protein
WebThis gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in spleen (RPKM 7.8), esophagus (RPKM 7.0) and 25 other tissues Orthologs mouse all NEW WebFERM domains are trilobed, typically N-terminal domains (Chishti et al., 1998). They are commonly found in proteins that bind cytoplasmic regions of transmembrane proteins …
Ferm domain-containing protein
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WebDescription: Homo sapiens FERM and PDZ domain containing 4 (FRMPD4), mRNA. RefSeq Summary (NM_014728): This gene encodes a multi-domain (WW, PDZ, FERM) … WebMay 31, 2011 · Protein names Recommended name FERM and PDZ domain-containing protein 2 Alternative names PDZ domain-containing protein 4 PDZ domain-containing protein 5C Gene names Name FRMPD2 Synonyms PDZD5C, PDZK4, PDZK5C Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic …
WebIn this paper, we focused on FERM domain-containing protein 5 (FRMD5), and confirmed that it is regulated by both b-catenin and TCF7L2. An additional reporter assay disclosed that a region in intron1 transcriptionally regulated the expression of FRMD5. ChIP assay also corroborated that TCF7L2 associates with this region.
WebFocal adhesion kinase (FAK) is a scaffold and tyrosine kinase protein that binds to itself and cellular partners through its four-point-one, ezrin, radixin, moesin (FERM) domain. Recent structural work reveals that regulatory protein partners convert auto-inhibited FAK into its active state by binding to its FERM domain. WebFeb 29, 2012 · The 714-amino acid FRMD7 protein shares close homology with FARP1 (602654) and FARP2 (617586) that is concentrated at the N terminus of the protein, where B41 and FERM-C domains are present. Expression analysis of FRMD7 showed that the mRNA is present in most tissues at low levels.
WebThe amino-terminal region of FAK contains a region of sequence homology with band 4.1 and ezrin/radixin/moesin (ERM) proteins termed a FERM domain. FERM domains are …
WebSep 9, 2024 · First, a key leucine residue (L353) in the SNX17 FERM domain involved in contacting the tyrosine in the NPxY/NxxY motif is an alanine in the SNX27 FERM domain. Importantly, an SNX17 FERM domain containing an L353A mutant was unable to interact with the NPxY-containing cargo P-selectin, further supporting the importance of this … jaywillz medicine mp3 download naijaloadedWebFeb 22, 2024 · The protein Na +, H +-exchanger 1 (NHE1) contains a positively-charged ERM-binding motif in the C-terminal cytoplasmic tail, which binds to the FERM domain of ezrin . The ERM proteins, especially ezrin, also directly bind to the P-glycoprotein (P-gp), which is a key player in multidrug-resistant phenotypes in cancer. jay x everyone ao3WebSep 9, 2024 · First, a key leucine residue (L353) in the SNX17 FERM domain involved in contacting the tyrosine in the NPxY/NxxY motif is an alanine in the SNX27 FERM … kuzco modern mini pendantWebOct 22, 2010 · The nature and functions of FERM domain-containing proteins (FDCPs) imply that FERM domains link the plasma membrane with cytoskeletal structures at specific cellular locations 1 by directly ... kuzco taro pendantWebFeb 29, 2012 · The 714-amino acid FRMD7 protein shares close homology with FARP1 ( 602654) and FARP2 ( 617586) that is concentrated at the N terminus of the protein, … jaywillz medicine mp3 download justnaijaWebThe FRMD7 gene provides instructions for making a protein whose exact function is unknown. This protein is found in many tissues, but it is most abundant in areas of the … jaywood manor drive brick njWebMar 21, 2024 · This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014] GeneCards Summary for FRMD4B Gene FRMD4B (FERM Domain Containing 4B) is a Protein Coding gene. jayxme dj