Cish isoforms
WebCIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in … WebEight SOCS proteins have been described, SOCS1–SOCS7 and CISH, and all share a central Src homology 2 domain, a SOCS box located at the C terminus, and an N-terminal domain that varies in length and function.
Cish isoforms
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WebThe protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein … WebKey features and details Rabbit polyclonal to CISH/CIS - C-terminal Suitable for: IHC-P, WB Reacts with: Rat, Human Isotype: IgG You may also be interested in Protein Recombinant Human CISH/CIS protein (ab117057) Primary Anti-C6orf134/TAT antibody (ab184778) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products …
WebSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 … WebAug 1, 2024 · Manipulation of intrinsic factors that inhibit T cell effector function and neoantigen recognition may therefore improve TIL therapy outcomes. We previously identified the cytokine-induced SH2...
WebFluorescence in situ hybridization (FISH) technologies enable rapid detection of chromosome aberrations in all manner of tissues, including both fresh and archival specimens. These technologies have gained broad acceptance in the clinical cytogenetic and research communities. WebNov 1, 2014 · The founding member of the SOCS family, cytokine inducible SH2-containing protein (CISH), and the seven other members present in mammals, SOCS-1 to -7, share a common structure. All SOCS proteins contain a central SH2 domain with an N-terminal extended SH2 subdomain (ESS) and a C-terminal 40 amino acid (aa) motif, the SOCS box.
WebThe expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. 7 results for "CISH".
WebOct 14, 2024 · CISH expression and inducibility in effector T cells To explore the pattern of CISH expression in human TIL, we performed single cell RNA sequencing (scRNAseq) … trump\u0027s secretary of stateWebHome / Human / CISH Antibody. Western blot analysis of extracts of 293T cells, using CISH antibody (15-585) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. … trump\u0027s secretary of hhsWebMar 28, 2024 · Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation mediated by PLC-γ1 regulation, and ... trump\u0027s secret chinese bank accountWebThe expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. For Research Use Only. trump\u0027s secretary of labor epsteinWebAnti-CISH antibody produced in rabbit. IgG fraction of antiserum, buffered aqueous solution. View Price and Availability. ... Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Immunogen. CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein. Sequence. Packaging. 50 μg. trump\u0027s secretary of transportationWebCISH is a highly sensitive and reliable method for detecting macrolide-resistant H. pylori in formalin-fixed, paraffin-embedded biopsy specimens, which represents the routine … trump\u0027s secretary of the interiorWebMultiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Chromosome. 3: Cytoband. p21.2: Chromosome location (bp) 50606490 - 50611831: Protein evidence: Evidence at protein level : ... CISH-001: ENSP00000294173 ENST00000348721: philippines is a disaster-prone country essay